SS-31 helps improve mitochondrial function and overall production of energy via ATP synthesis. Research has shown its ability to reduce inflammatory cytokines which cause oxidative stress and inflammatory diseases such as Alzheimer’s, Parkinson’s, heart disease, diabetes, kidney disease, and more
 
Improved Mitochondrial Function: SS-31 enhances ATP production and mitochondrial respiration, addressing dysfunction in conditions like Barth syndrome, heart failure, and age-related decline. It improves energy output, which may alleviate fatigue and boost physical and mental endurance.
Anti-Aging and Muscle Performance: In aged mice, SS-31 reverses sarcopenia, improves exercise tolerance, and restores skeletal muscle function by reducing oxidative stress and stabilizing mitochondrial membranes. This suggests potential for improving mobility and quality of life in elderly humans.
Neuroprotection and Cognitive Support: SS-31 may protect against cognitive decline in neurodegenerative diseases like Alzheimer’s by reducing neuroinflammation, stabilizing mitochondrial function, and enhancing BDNF signaling, which supports synaptic plasticity and memory. Studies in mice show improved cognitive function and motor skills.
Cardiovascular Health: SS-31 protects against heart failure, hypertrophic cardiomyopathy, and ischemia-reperfusion injury by improving mitochondrial energetics and reducing oxidative damage. It may also lower inflammation, supporting heart health in conditions like hypertension or diabetes.
Kidney Protection: SS-31 mitigates renal damage in conditions like diabetic nephropathy and acute kidney injury by reducing oxidative stress, preventing apoptosis, and improving mitochondrial morphology. It shows promise for preserving kidney function.
Anti-Inflammatory Effects: By reducing mitochondrial reactive oxygen species (ROS) and modulating pathways like NFκB, SS-31 decreases inflammation in conditions such as sepsis, diabetes, and cigarette smoke-induced damage.